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Galantamine plasma concentrations may be increased in patients with moderate to severe hepatic impairmentsee section 5.2
The occurrence of nausea is shown to correlate with higher peak plasma concentrationssee section 4.5
There is no rebound effect after abrupt discontinuation of treatmente.gin preparation for surgery
The pharmacokinetics of galantamine in subjects with mild hepatic impairmentChild-Pugh score of 5-6were comparable to those in healthy subjectsIn patients with moderate hepatic impairmentChild-Pugh score of 7-9AUC and half-life of galantamine were increased by about 30see section 4.2
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