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Isoniazid is considered to be unsafe in patients with porphyria although there is conflicting experimental evidence of porphyrinogenicity.

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Tell your doctor and pharmacist if you are allergic to isoniazidany other medicationsor any of the ingredients in isoniazid tablets or oral solutionAsk your pharmacist for a list of the ingredientstell your doctor and pharmacist what other prescription and nonprescription medicationsvitaminsnutritional supplementsand herbal products you are taking or plan to takeBe sure to mention any of the followingacetaminophenTylenolantacidscarbamazepineCarbatrolEquetroTegretolotherscitalopramCelexaescitalopramLexaprofluoxetineProzacSarafemSymbyaxfluvoxamineLuvoxketoconazoleNizoralparoxetinePaxilphenytoinDilantinPhenyteksertralineZolofttheophyllineElixophyllinTheochronTheo-24and valproic acidDepakeneDepakoteMany other medications may interact with isoniazidso be sure to tell your doctor about all the medications you are takingeven those that do not appear on this listYour doctor may need to change the doses of your medications or monitor you carefully for side effectsin addition to the conditions listed in the IMPORTANT WARNING sectiontell your doctor if you have or have ever had kidney diseasediabetestinglingburningand pain in the fingers or toesperipheral neuropathyor human immunodeficiency virusHIVtell your doctor if you are pregnant or plan to become pregnantIf you become pregnant while taking isoniazidcall your doctoryou should know that you should not drink alcohol while taking this drug.

Symptoms of an isoniazid overdose include nauseavomitingdizzinessslurring of speechblurred visionvisual hallucinationsseizurescomaand death.

Your doctor may want you to have blood tests or other medical evaluations during treatment with isoniazid to monitor progress and side effects.

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check for contraindications to the administration of isoniazid for preventive therapy.

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